The hottest smartphone will open the next applicat

Intelligence will open the next application platform in biomedical field

can intelligence only be used for communication and entertainment? Nowadays, with the advent of the intelligent era, it is not only used for communication and entertainment, but also for portable laboratories and the addition of inspection and detection functions, which make them more powerful. The intelligent devices carried on the are refreshing the previous research results

drug resistance detection of bacteria

drug resistant bacteria have strong viability and high resistance to antibiotics. Due to the lack of professional equipment and technicians in many remote areas to detect the drug sensitivity of bacteria, high mortality diseases such as pneumonia and sepsis occur frequently. To this end, a team from UCLA has developed a low-cost simple attachment that can automatically detect bacterial resistance

it is reported that the accessory will be connected with the 96 well plate, the sample will be illuminated by the LED light, and then the light transmittance change caused by the sample under different concentrations of antibiotic drugs will be scanned by the camera. Finally, the photos will be sent to the remote server for antibiotic sensitivity testing, and the test results will be sent back to China about 1 minute later

according to Aydogan ozcan, Professor of electrical engineering and bioengineering Department of UCLA Herry Samueli School of engineering and applied engineering, this new detection method can carry out laboratory level tests in a wide range of areas, so it is extremely suitable for those areas where medical resources are scarce

portable laboratory

the detection of cancer was once a very complex work. In order to get the test results quickly, Lei Li of Washington State University and his research team developed a low-cost portable laboratory, which is said to be able to analyze a variety of samples at the same time to accurately capture a cancer biomarker and give the laboratory test results

the laboratory is mainly composed of intelligence and an eight channel intelligent spectrometer that can detect human interleukin-6. Compared with ordinary spectrometers, the multi-channel spectrometers developed by Li team can detect up to 8 different samples at one time by using a common colorimetric test method called enzyme-linked immunosorbent assay (ELISA), in which antibodies and color changes are identified as disease markers

li indicates that the equipment can make 8 different samples undergo the same test, or put a sample into 8 different holes for 8 different tests, which greatly improves the efficiency of product detection, and the accuracy is as high as 99%

microscopic detection of skin cancer

there are more than 2million skin cancer patients in the world every year. In order to help some remote areas lacking high-performance microscopes complete the detection of canceration of skin samples, researchers from the University of Texas Houston Health Science Center developed a simple microscope

the microscope is mainly composed of intelligent and 3mm spherical lens. Researchers used the equipment to analyze 1021 sample slides. The results showed that the detection rate of cancer was as high as 95.6% for basal cells and 89% for squamous cell carcinoma before the enterprise opened

in general, at present, this device is mainly suitable for detecting patients with non melanoma skin cancer, with an accuracy rate of 90%, while the accuracy rate for patients with melanoma skin cancer is only 60%. More in-depth research is needed to enhance the intelligent detection rate. But in any case, mobile devices have shown great potential in the field of skin cancer, and may also play a role in the detection of more other diseases in the future

quantitative detection of nucleic acid molecules

the method of detecting disease molecular markers is very complex and expensive, which often needs to be carried out in the laboratory, which greatly reduces the diagnostic efficiency. The new mileage of Caltech in the next seven years will reach more than 30000 kilometers. Professor Rustem ismagilov of the Department of chemistry and chemical engineering and his team are developing a diagnostic technology for on-site real-time detection, which can complete quantitative detection with the help of cameras

this technology uses a microfluidic technology platform called slipchip. Researchers put special chemical indicators into the micropores of slipchip equipment. After isothermal amplification reaction, the micropores will change color accordingly according to whether a positive reaction or a negative reaction occurs. For example, if it is used to count HCV RNA molecules in the sample, the micropores containing this RNA molecule will become blue because the molecule will be amplified during the reaction, while the micropores without this RNA molecule will remain purple

then the user only needs to take the whole reaction result and process it according to a certain ratio measurement method, so that the color detected by the camera can be converted into a clear positive and negative readout value

prevention of diabetes foot ulcer

patients with diabetes often need regular examinations to monitor the formation of foot ulcer. Their symptoms are mainly manifested in foot structural deformation, excessive pressure and poor blood supply capacity. Nearly 130million people around the world are affected to varying degrees, and those who are serious will face the risk of amputation

however, ulcers can usually be detected only after formation, which not only requires a lot of treatment time, but also brings greater economic burden to patients. In order to be able to perceive the possibility of patients' foot ulcer in advance, Danny Bavli and his team from Hebrew University in Jerusalem, Israel, developed an intelligent machine washable sock called sensego

sensego has dozens of micro processed pressure sensors. Changes in pressure on the feet of patients due to incorrect posture, structural deformation or unfit shoes will be recorded as electrical signals and transmitted to relevant applications on intelligence to systematically calculate whether patients are at risk of foot ulcer. Danny Bavli said, "through such a simple and effective prevention method, we can significantly reduce the treatment pressure of diabetes patients."

DNA scanning microscope

the Aydogan ozcan research team from the Howard Hughes School of medicine at the University of California, Los Angeles has developed a new accessory that can use intelligence as a DNA scanning microscope

according to ozcan, this is an optical accessory, or a small 3D printing box, which includes components such as lens, filter, bracket and laser diode. It can measure and image DNA 50000 times thinner than human hair. The application uses the camera to scan DNA molecules, transmit the data information to the remote server to complete the measurement, and finally return the measurement results. The whole process is said to be less than 10 seconds

compared with the expensive and bulky traditional microscope, the new DNA detection technology born around intelligence not only saves costs, but also further promotes the development of telemedicine and mobile medicine

diagnose HIV and syphilis

disease types such as HIV and syphilis and the cancer mentioned above often have a long incubation period. It is obviously too late to treat them until the complete outbreak. If there is a simple and convenient product that can detect diseases anytime and anywhere, the risk of such diseases will undoubtedly be greatly reduced

researchers from Columbia University jointly developed a low-cost intelligent adapter, which can complete the diagnosis of HIV and syphilis in only 15 minutes. They transplanted a complete immunoassay program that meets the laboratory standard into the accessory. This adapter can replicate all the mechanical, optical and electronic functions of laboratory based enzyme-linked immunosorbent assay (ELISA), which is powered by. The data generated by the test will be sent to the memory through the audio interface

according to the test of the R & D team, they conducted a triple immune test on the accessory: simultaneously detect HIV antibody, Treponema pallidum specific antibody and non Treponema pallidum antibody against syphilis. The overload protection function after 15 minutes · output experimental report · comparison between energy-saving test results and laboratory test results is realistic. The sensitivity of HIV ELISA and rapid plasma reaction (syphilis screening test) of the adapter is 92-100%, and the specificity is 79%-100%, which is consistent with the current clinical algorithm requirements

compared with the testing equipment in the laboratory, which is prone to tens of thousands of dollars, this adapter is light and compact, with low power consumption, and the manufacturing cost is only about $34. At the same time, according to the survey of corresponding patients, 97% of patients are willing to use this kind of equipment

mobile devices will become a new interface for biomedicine

although some of the above research results have not been officially put into use, and they have obvious limitations compared with the functions at the laboratory level, they all more or less reflect the embryonic form of the combination of consumer electronics and laboratory level medical testing projects. Intelligence has become the latest interface for the Internet and even finance, e-commerce, entertainment and other industries, and the biomedical field seems to be facing the same changes. Especially in foreign countries, this trend has become more and more obvious. People are more inclined to use applications to achieve health care functions. The number of mobile medical enterprises is gradually increasing, and the service items are becoming richer. In the future, perhaps the concepts of telemedicine and mobile medicine will be popularized rapidly, and physical medical institutions will also face transformation

comments

with the advent of intelligent and pocket technology, intelligence has more uses to detect blood glucose and release ldquo; by administrative means; The power of famine rdquo; It is more convenient to analyze and test the composition of substances. The multi-functional inspection and detection instrument carried on the machine makes the experimental work more flexible and has a more convenient way at the same time